What Will We Carry Forward from This Time?

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What Future Will We Choose for Physics?

Science in the United States is in a time of pain and uncertainty. The pain is felt most acutely by young scientists, who are having great difficulty establishing their careers. The uncertainty about the duration and outcome of the current situation stems from its roots in ponderous events of recent history—the end of the cold war, industrial downsizing, government deficits and demographic tren...

I Will Forgive You--This Time.

Although adenocarcinoma of the prostate persists in being the most common form of cancer in men, its clinical behavior does not maintain this type of consistency, wavering from extremely aggressive fatal cancers to clinically insignificant, incidental entities. The prevalence of prostate cancer at autopsy is remarkably high, increasing from 20% in men in their 50s to up to 80% in men 70 to 80 y...

COPD heterogeneity: what this will mean in practice.

COPD is a complex collection of conditions. All share the feature of limited expiratory air flow. It is a "disease" in the same sense as is "chronic renal failure." Like most other chronic organ failure "diseases," COPD has disparate causes, and patients are heterogeneous in their prognosis and response to treatment. Unlike many other diseases, the heterogeneity of COPD is just beginning to be ...

The origin of life: what we know, what we can know and what we will never know

The origin of life (OOL) problem remains one of the more challenging scientific questions of all time. In this essay, we propose that following recent experimental and theoretical advances in systems chemistry, the underlying principle governing the emergence of life on the Earth can in its broadest sense be specified, and may be stated as follows: all stable (persistent) replicating systems wi...